El Payo (Payu in extremaduran) is a village and municipality in the province of Salamanca, western Spain, part of the autonomous community of Castile-Leon. It is located 135 kilometres from the provincial capital city of Salamanca and has a population of 448 people.
The municipality covers an area of 61.87 km².
It lies 934 metres above sea level.
The post code is 37524.